Recent reports caution about the increasing use of Botox – the drug that erases wrinkles and treats muscular disorders. The treatment so far was considered relatively harmless and temporary solution to ailments real and imagined.
However, the latest feature article in The Guardian by Alison Moodie reports about the new study in the University of Wisconsin-Madison that has raised fresh doubts about how Botox works in the body. Contrary to notions that it stays put at the injection site, researchers found evidence from animal tests that the drug was in fact able to move between nerve cells.
This is not the first sign of concern about Botox procedure. The US Food and Drug Administration (FDA) had a safety warning issued in 2009, that said the toxin “may spread from the area of injection to produce symptoms of botulism”, including muscle weakness and difficulty breathing that can occur hours or weeks after an injection.
Earlier in 2002, the FDA approved the drug to be used cosmetically to minimize facial wrinkles, primarily the vertical lines between the eyebrows. Meanwhile, Botox sales, a little over $ 300 million in 2001, jumped to $ 1.9 billion last year.
The Wisconsin study set out to test whether the toxin remains in the injected area, or whether it has the ability to travel. The researchers looked at two strains of botulinum toxin. Using mouse neurons, they showed that the toxin molecules were able to move between different nerve cells in a lab dish.
“Once these toxins enter a neuron, a fraction of the toxin acts within that neuron, but another fraction is able to move – from the first neuron – into connected neurons,” said senior author Edwin Chapman, an investigator at the Howard Hughes Medical Institute and professor of neuroscience at the University of Wisconsin-Madison. “In other words, these toxins do in fact move about among connected networks of neurons.”
Dealing with most of the skin disorders with natural procedures, Herbally Radiant has been highlighting the potential health risks from surgical procedures like Botox injections and injecting dermal fillers. The only difference is that while such surgical procedures are expected to show instant results, the herbal natural skin care products need time to work on skin. But, unlike the temporary results from Botox or dermal filler, the organic ingredients in the natural products create more durable effects that add to the overall beauty and general appearance.
Another adverse reaction conveyed by a mature customer on frequent Botox treatment was that “being unable to move your face emphatically, as you listen to someone speak, reduces feelings of connection. In essence, numbing your face very likely numbs your emotions: Botoxed subjects show less brain-scan activity in key emotional regions … All in the quest for a youthful face for others to gaze upon! And then what? Confronted with a motionless face, one that expresses nothing as we speak to its owner, we humans feel confounded, disconnected, and distressed.” Well, this view is not without substance.